be tied to heart health; high levels are considered a risk factor for cardiovascular disease. They might take it for insulin resistance/PCOS issues, or they might take it for blood sugar issues...both, since the two are often related. There is some research indicating that administration of B-group vitamins reduces homocysteine levels in non-pregnant PCOS patients treated with metformin. But we don't really know yet if lowering homocysteine levels results in any meaningful reduction in long-term endpoints like decreased heart attacks or mortality. All this information about metformin impacting B12 and folic acid levels makes me wonder if there are special implications for women of childbearing age. We know that folic acid levels are important for preventing birth defects like neural tube defects (NTDs, like spina bifida or anencephaly). If a woman with PCOS has been on metformin for years and her folic acid levels are chronically low when she conceives, does this increase her risk for NTDs? There doesn't seem to be any increase in birth defects in women on metformin so far, but research is limited. doxycycline when to take It's great that now we have not only a good choice of different medication for all cases but also a choice of really effective medications that naturally improve our life. I have been suffering from asthma since 1990, probably that was a consequence of living in a big city (later I moved from Boston to New Haven) or may be that was hereditary as my grandfather died from an uncontrolled asthma attack. At those time people had little choice and when conventional drugs couldn't help them they were kind of doomed. But even now you have to be patient until you find your medication that will help you without causing dramatic side effects. Before I changed my doctor and the new guy prescribed me with Ventolin I have tried many different bronchodilators but only some of them were more or less effective and even a smaller amount were both effective and harmless. Every time I used to wake up breathless in the middle of the night I thought that I won't see the daylight anymore. But now with Ventolin I am no longer afraid of night attacks. Cipro otic Don't know why, but I just ran a search for metformin and spina bifida. I was on metformin and chlomid 3 months before conceiving. My dr. kept me on metforming for 16 weeks into pregnancy with twins and one of my twins was born with L3-L5 myelo spina bifida. I've always wondered if there was a connection. December 1, 2010 at AM valtrex monograph Metformin is for women with diabetes and women that have PCOS. I never heard of it being the cause of twins.-- Jul 26, 2001. By Hazel Muir. Pregnant women who take the recommended folic acid supplements may be more likely to have twins, say researchers in. Twin pregnancy is found among people who take Metformin, especially for people who are 30-39 old , have been taking the drug for 1 - 2 years, also take medication Saxagliptin, and have Ovulation induction. This study is created by e Health Me based on reports of 251,352 people who have side effects when taking Metformin from FDA, and is updated regularly. Metformin has active ingredients of metformin hydrochloride. (latest outcomes from Metformin 259,096 users) Twin pregnancy (two babies in uterus) has been reported by people with hiv infection, birth control, multiple sclerosis, ovulation induction, crohn's disease (latest reports from 1,022 Twin pregnancy patients). Twin pregnancy (386 drugs) Twin pregnancy (213 conditions) NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. DISCLAIMER: All material available on e Health is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Can anyone tell me if Clomid plus Metformin increases or decreases your chance of multiples? Met works on your endocrine system to even out blood sugar. I just want to have a baby-- no preferrence here, but would like some information! So- multiple moms and singleton moms- please reply! yetanothertripletmom-- I'm not sure I understand your answer. Excess blood sugar CAN (but not always) cause blood restrictions in the uterus resulting in no implantation of the embryo or a miscarriage. I'm not sure what your aim is in taking both, maybe your doctor can clear up any questions or concerns you. Yes, we conceived actually 3 times with the combo of metformin and clomid (second one ended in a miscarriage around 6 weeks). Perhaps I should clarify-- I've heard that Clomid alone increases your chances, but adding Metformin DECREASES your chances (of multiples). Also, Melissa, did you conceive both times with the combination? I was put on both because it can aid in ovulation for those who have PCOS ( I don't ovulate at all on my own). I don't have a preference, as explained, but bottom line: I want a healthy pregnancy and healthy baby as the result-- one, two, three, twelve-- whatever God blesses me with. Clomid and metformin do completely separate things. I was told by a friend that Clomid causes hyper-ovulation (as confirmed by my ob/gyn) but I've heard (through a friend) that the Metformin will limit the chance of multiples (not sure how). I'm going to ask my doc at the next appt, but wanted to ask ahead of time from those with experience-- hope that's alright. Also, I have astronomically high testosterone numbers, causing the lack of O as well as the blood sugar surge. Either way, I've already learned that this whole fertility drug thing is a c___p-shoot at best. Metformin twins Clomid Metformin Twins BestPrices! -, Metformin and Multiples? - BabyCenter Metformin meal plan Tamoxifen or femara Tamoxifen sigma Metformin clomid twins with expert advice and information on diseases, medical conditions, medications and mental health. Learn of new discoveries in health and medicine. View mobile site Metformin clomid twins - A Generic Treating. Folic acid may raise chance of twins New Scientist Risk of Twins/Triplets After Ovulation Induction The methodologies of thiazide on effective areas of metformin b-12, dose, and femara and metformin twins pakage were re-analysed following pdr for. where to buy cytotec in hong kong Metformin is a glucose-lowering drug, which is used in the treatment of type 2 diabetes. During the last decade the pharmacogenetics of both the. A clomid+metformin combination is next down on the list, while metformin alone carries the lowest chances of twinning. So, while clomid+met has higher chances than a natural/unmedicated cycle, having the met makes the odds thankfully lower than taking clomid alone.