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    Ordering any prescription drugs through the mail or Internet from other countries is illegal and risky. Check this list of other big-name drugs that will soon be available as generics.) You can legally take your prescription to a brick-and-mortar drugstore in Canada, although that’s not a convenient option for most people. There’s just no way of knowing that the drugs are safe, or work as they are supposed to. Canadian pharmacies are subject to robust laws similar to those in the U. But ordering drugs from Canada—or any other country—is a bad idea for several reasons. If it’s cost savings you’re after, you’ll be glad to know that the arthritis drug Celebrex (celecoxib) was recently approved by the FDA to be sold as a generic. First of all, it’s impossible to know what you are getting. “Most internet pharmacies claiming to be Canadian are not,” Carmen Catizone, executive director of the National Association of Boards of Pharmacy, said. “The Food and Drug Administration does not have jurisdiction over prescription medications from other countries and, therefore, cannot guarantee their safety and effectiveness,” according to a spokesman for the agency. So if there’s a problem with a medication or the way a prescription was filled, you have little or no recourse. Many stores offer discounted, generic drug programs where you could get your medication for as little as $4 a month or $10 for three months. “Frequently, they are fake storefronts selling cheap generics from third world countries.” The drug could be old, improperly stored or manufactured, adulterated, or even fake. Similarly, the Canadian government has washed its hands of any responsibility for drugs shipped to the U. In general, instead of bargain-shopping for prescriptions overseas, it’s a better idea to ask your doctor or pharmacist about money-saving options at legitimate U. Some pharmacies also offer additional loyalty programs where members can receive discounts on other generics or even brand-name medications. Up to 80 percent of drugs from some countries are counterfeit, according to the World Health Organization. If you order online for convenience, stick with online drugstores that you already know and trust—such as the chain drugstores, big-box stores, or your local, mom-and-pop pharmacy. Otherwise, check that your pharmacy is licensed, situated within the U. For guidance, check NABP's Verified Internet Pharmacy Practice Sites program, which lists safe pharmacies. metformin 1000 mg price To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more CELECOXIB (sell a KOX ib) is a non-steroidal anti-inflammatory drug (NSAID). This medicine is used to treat arthritis and ankylosing spondylitis. It may be also used for pain or painful monthly periods. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. They need to know if you have any of these conditions: -asthma -coronary artery bypass graft (CABG) surgery within the past 2 weeks -drink more than 3 alcohol-containing drinks a day -heart disease or circulation problems like heart failure or leg edema (fluid retention) -high blood pressure -kidney disease -liver disease -stomach bleeding or ulcers -an unusual or allergic reaction to celecoxib, sulfa drugs, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding Take this medicine by mouth with a full glass of water. Take it with food if it upsets your stomach or if you take 400 mg at one time. Try to not lie down for at least 10 minutes after you take the medicine. Do not take more medicine than you are told to take.

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    Celebrex, a prescription pain medication in the same class as Vioxx, which was pulled from the market in 2004 over cardiovascular concerns, is as safe as over-the-counter (OTC) pain medications. However, you may want to think twice before switching from Advil or Aleve to Celebrex. The somewhat surprising finding is the result of a 10-year study conducted by Pfizer, the maker of Celebrex, involving more than 24,000 people with arthritis who either had heart disease or were at high risk for it. They were given either Celebrex (celecoxib), a drug known as a COX-2 inhibitor, Advil (ibuprofen) or Aleve (naproxen). The latter two are available OTC and are known as NSAIDs (non-steroidal anti-inflammatory drugs). Although the study was funded by Pfizer, the lead author was Steven Nissen, MD, a cardiologist at the Cleveland Clinic, who was one of the first physicians to sounds alarms about links between Vioxx and an increased risk of heart attack and stroke. Published in the New England Journal of Medicine, the study not only found that all 3 medications had similar efficacy, but all had nearly the same rate of heart disease, heart attack or stroke from taking it. Nearly a decade after reports first surfaced linking the prescription pain reliever celecoxib (Celebrex) to an increased risk of heart attack, and two years after the American Heart Association (AHA) warned against the drug for people at risk of heart problems, about 11 million prescriptions for it are still filled each year, often for arthritis, menstrual cramps, and acute pain. Well, maybe it's no coincidence that Pfizer, maker of celecoxib, has resumed heavily advertising it directly to consumers, spending $54.8 million on ads in 2007 and $58.5 million in 2008. A new ad—a full two minutes long, and also available online at a man walking a dog and riding a bike. It suggests that the drug is no riskier than other related nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil and generic) and naproxen (Aleve and generic). While celecoxib may be appropriate for a small number of patients, our reservations about it remain strong. Although the evidence is mixed, some meta-analyses, which assess the combined data from many clinical trials, have linked celecoxib at higher or more frequent doses to an increased likelihood of heart attack compared with either a placebo or naproxen. Indeed, the government's Agency for Healthcare Research and Quality now says that naproxen is less likely than other NSAIDs to harm the heart. And the AHA says celecoxib should be used to treat people at risk of heart attack only if other measures have failed. That recommendation is based mainly on the ways that celecoxib acts in the body, which in theory may harm the heart more than other NSAIDs. An unfortunate effect of all NSAIDs is that they block production of an enzyme that normally protects the lining of the stomach from stomach acid.

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