It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Will plaquenil help lupus when you have sjogrens Plaquenil drug monitoring Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Unfortunately, it's not a good idea to stop methotrexate "cold turkey.". Some people experience no side effects to suddenly stopping taking this medication, but it does have the potential for creating an intense RA flare. The goal of medication is to protect your joints and other systems in the body internal organs, such as the heart. It would be unlikely IMO that the Plaquenil is the cause, since there is tapering necessary when stopping it and no documented 'withdrawal' syndrome associated with it. If you have taken it for a long time, it is probably not even out of your system yet, since Plaquenil has a half-life of 30-60 DAYS not hours. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Is it necessary to wean off of plaquenil Going off Plaquenil - Sclero Forums MAIN - Sclero Forums, What Are The Side Effects Of Stopping Methotrexate? Plaquenil difficulty sleeping The most important factor is early diagnosis and aggressive treatment. “When treated early with DMARDs and biologics, remission rates can exceed 60%,” says Paul Emery, MD, director, Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, United Kingdom, and one of the authors of the ACR/EULAR definition. Your RA is in Remission! Now What? Arthritis Foundation. Plaquenil Withdrawal?. The Risk of Retinal Toxicity with Plaquenil. Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. Though Plaquenil is generally regarded as safe during pregnancy, it is recommended that effective birth control is used throughout the course of Plaquenil treatment and for up to six months after treatment is stopped.