Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine toxic retinopathy Chloroquine kinase Plaquenil treatment sle Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine may inhibit P-glycoprotein P-gp. Digoxin is a substrate for P-gp transport. For patients on a stable digoxin regimen and initiating hydroxychloroquine, no initial dose adjustment of either drug has been advised; however, serum digoxin concentrations should be monitored and used for digoxin dose titration as clinically. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil staggered dose Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil hydroxychloroquine sulfate dose, indications. Plaquenil for ulcerative colitisDoes plaquenil cause sun sensitivityRetinal toxicity plaquenilDifference between chloroquine and quinineWhich autoimmune not treat with plaquenil Apr 10, 2019 To treat malaria Plaquenil is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Use protective clothing. Plaquenil Uses, Dosage & Side Effects -. Plaquenil Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Plaquenil. Jan 03, 2020 Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine retinopathy is most influenced by daily dose and duration of use. Risk for toxicity is less with 5.0 mg/kg real weight/day for hydroxychloroquine and 2.3 mg/kg real weight/day for chloroquine. Patients are at low risk during the first 5 years of treatment.