Chloroquine hydrochloride tablets

Discussion in 'Northwest Pharmacy Canada' started by vasyan, 23-Feb-2020.

  1. Winterborn Guest

    Chloroquine hydrochloride tablets


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Sulfate, and chloroquine hydrochloride related to the Biopharmaceutics Classification System BCS are reviewed. The available information indicates that these chloroquine salts can be classified as highly soluble and highly permeable, i.e. BCS class I. The qualitative composition of immediate release IR tablets containing these Active Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine hydrochloride Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine hydrochloride tablets

    Chloroquine Hydrochloride Drug Information, Professional, Chloroquine Dosage Guide with Precautions -

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  6. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.

    • Chloroquine - Wikipedia.
    • Chloroquine hydrochloride - DrugBank.
    • Drug Information Portal - U. S. National Library of..

    Chloroquine hydrochloride Injection 50 mg/ml 40 mg/ml base chloroquine phosphate Tablets 250 mg 150-mg base; 500 mg 300-mg base Indications and dosages Suppressive prophylaxis. Adults 500 mg 300-mg base P. O. on same day once weekly beginning 2 weeks before exposure. Chloroquine Phosphate Dosage and Administration Administration. Administer orally. 136. Oral Administration. Administration with a meal may minimize adverse GI effects. 121 134. For prevention of malaria, give once weekly on same day each week. 136. Dosage. Available as chloroquine phosphate; 136 dosage usually expressed in terms of chloroquine. This study aimed to evaluate the quality of Chloroquine CQ tablets available in selected African countries. Twenty-six samples of antimalarial CQ tablet of 100, 150 and 250 mg were collected from 12 African countries and evaluated for their quality in the Drugs Quality Control Laboratory of Rabat, Morocco.

     
  7. skitnik XenForo Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Features distinguishing amoebic from pyogenic liver abscess. Amebic Abscess of the Liver Treatment Failure With. Amoebic Liver Abscess -
     
  8. TPAKTOP New Member

    Hydroxychloroquine Plaquenil Success, Reviews and Side Effects Can hydroxychloroquine cause liver damage? Elevated liver enzymes are a common problem in some patients being treated with hydroxychloroquine, such as patients with lupus. However, as a general rule, hydroxychloroquine is not associated with an elevation in liver enzymes when used to treat autoimmune and rheumatologic diseases.

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