I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Norethindrone and plaquenil Biaxin bactrim plaquenil for bartonella Can generic plaquenil cause diarrhea G6pd hydroxychloroquine If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Stop taking the medicine and. We study how severe was Withdrawal syndrome, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Plaquenil side effects when stopping Side effects to Stopping Plaquenil. - Sarcoidosis - Inspire, Withdrawal syndrome in Plaquenil how severe and when it was. Hydroxychloroquine sulfate solubility I have been on the plaquenil 200 mgm for about 4 months now. I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Noticed nothing different. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Let me tell you what weaning down from Plaquenil is like.. Plaquenil Side Effects - GoodRx. Taking Plaquenil for Rheumatoid Arthritis. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Like I have pressure on the top of my head. I nver had this before. Could this be a side effect of the Plaquenil and does it normaly go away after I take it for a while? Answer. That is an unusual side effect for Plaquenil. I would try stopping and restarting it to make sure Plaquenil is at fault.