It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine cytotoxic falicparum Uniquin hydroxychloroquine Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Plaquenil is a prescription medication approved by the Food and Drug Administration FDA to treat inflammation associated with lupus in people whose symptoms have not responded to drugs with lower risk for side effects. Plaquenil is also known by its drug name, Hydroxychloroquine. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine lupus Atrial Fibrillation, Hydroxychloroquine, and Lupus - LupusCorner, Plaquenil Hydroxychloroquine MyLupusTeam How long for plaquenil drug eruption to go awayIs chloroquine-primaquine capitalizedRates of plaquenil toxicity Mechanism Hydroxychloroquine is thought to improve symptoms of systemic diseases by preventing inflammation. For example, to treat both rheumatoid arthritis and systemic lupus erythematosus SLE, it has been hypothesized that the drug suppresses T-lymphocytes by increasing the pH inside lysosomes, which disables leukocyte chemotaxis. Hydroxychloroquine - American Osteopathic College of.. Hydroxychloroquine MedlinePlus Drug Information. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis. What kind of medicine is hydroxychloroquine? Some medicines can slow down your lupus. Doctors call these DMARDs. This stands for Disease-Modifying Anti-Rheumatic Drugs. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work?