It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine sul tabs 200 mg Plaquenil cause constipation Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. Objective To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. An African American woman, aged 50 years, presents with painless “bruises” on her leg. She first noticed bruises on both legs a year ago and reports that they have since become larger. Easy bruising sometimes indicates a serious underlying condition, such as a blood-clotting problem or a blood disease. See your doctor if you Have frequent, large bruises, especially if your bruises appear on your trunk, back or face, or seem to develop for no known reasons For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil induced bruising on shins Lupus-Specific Skin Disease and Skin Problems Johns., Painless, bruise-like hyperpigmentation on a woman with. Chloroquine drug resistance Jan 11, 2015 I've taken Plaquenil for aprx 9 years. I have many complications w the diseases themselves but i bruise very easily. I also notice bruises that I cant explain. They all seem to be extra sore and very bright blue. I've ask my RA Dr about this but never a understandable explanation. Most of my bruising is found on my arms, hands and lower legs. Has anyone taking Plaquenil ever experienced bruising under.. Easy bruising Why does it happen - Mayo Clinic. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Erythema nodosum can go away on its own in three to six weeks. After it's gone, it may leave only a temporary bruised appearance or a chronic indentation in the skin where the fatty layer has been. WebMD's guide to the symptoms of lupus. When you have lupus, something happens to your body’s natural defense system your immune system to make it work incorrectly. Instead of only targeting.