These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Ophthalmologic complication of hydroxychloroquine What medicinescannot be taken with plaquenil Chloroquine side effects psoriasis Plaquenil use in patients He should not have these pills without your knowledge, they are only used for serious medical issues that you would know about. My guess is he might have been given it by a friend who told him it would get him high, because after all, kids are pretty dumb sometimes and don't realize how dangerous these medications can be. Thanks Jodie, I always take it with a meal. I have High BP and also atrial tachycardia and take two tablets for those conditions wich I take at the same time as the Hydroxychloroquine. I just wondered if perhaps I should separate them and take the Hydroxychloroquine in the evening to see if that would help. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Pill findercan u get high on hydroxychloroquine DailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet, Hydroxychloroquine I take Hydroxychloroquine 20. Plaquenil how does it workChloroquine falciparum targetChloroquine phosphate price Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil Dosage Guide -. Plaquenil hydroxychloroquine Basics, Side Effects.. You would not get any buzz. You might feel the effects, but there would not be any buzz like the one you get on other drugs such as Valium or Xanax. I once tried Zoloft and did not feel a thing. I then tried Xanax, and the high which I got was incredible. I tried Zoloft again to make sure that I was okay and the drug was a dud, but got no high. I take both minocycline and plaquenil. I tried weening myself off the plaquenil, but, couldn't take the pain. I've only been on the mino since February. But, so far I've had more good days than bad. And, that's a great thing. This time last year I believed my active days were over. I wasn't able to get out of bed for more than an hour at a time. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil?