Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Allergy signs to hydroxychloroquine Drug metabolism of plaquenil Does hydroxychloroquine cause fatigue Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Plaquenil Often plaquenil side effects do go away after a few weeks if you persist with the drug. Plaquenil is the only drug i have EVER had side effects to. I lost my appetite, had slightly blurred vision, had worsening peripheral neuropathy, felt nervous and anxious. I was ready to.took a good three weeks. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina 1 Contents Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects neuropathy Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Can Plaquenil cause Peripheral Neuropathy? Plaquenil for itp 1 80 After 2 weeks, the patient developed severe corticosteroid-induced side effects psychosis, insomnia, memory loss, muscle weakness, and weight gain. He discontinued the drug and did not come for a follow-up visit until 1994. At that time, he had been receiving no treatment for more than a year. Effectiveness of Chloroquine and Hydroxychloroquine in.. Hydroxychloroquine toxicity - EyeWiki. Hydroxychloroquine Side Effects, Dosage, Uses, and More. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Insulin or antidiabetic drugs As Plaquenil may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Drugs that prolong QT interval and other arrhythmogenic drugs Plaquenil prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term.