Although it is uncommon, lupus can also attack a patient’s liver, causing a more pronounced elevation in liver enzymes, such as ASTs and ALTs. When this happened to me, my symptoms included pervasive malaise, nausea, itching, and worsening of my overall health and lupus activity. Chloroquine generic name Plaquenil and tinnitus Chloroquine hemozoin falciparum Plaquenil Hydroxychloroquine may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Liver enzymes are present in liver cells and are spilled out into the bloodstream when there is an injury or illness to the liver. According to the Mayo Clinic, the two most common liver enzymes that are released and tested for are alanine transaminase, or ALT, and aspartate transaminase, or AST. Elevated liver enzymes often indicate inflammation or damage to cells in the liver. Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, elevating liver enzymes on blood tests. The elevated liver enzymes most commonly found are They consulted and referred me to a gastroenterologist. My family doctor was persistent in finding an answer, and wouldn’t let my rheumatologist rest until they found one. Plaquenil and liver enzymes Plaquenil for Hypercalcemia - Sarcoidosis - Inspire, Rheumatoid Arthritis & Elevated Liver Enzymes Healthfully Plaquenil and cotrimoxazoleChloroquine base molecular weightPlaquenil lupus pregnancy They never could figure out why. I was on CellCept at the time, but I was still on it when they stopped, so who knows. As for the liver, well I'm dealing with the same thing. I've got elevated liver enzymes currently. They told me I just have a fatty liver, and that it could actually be because of my Prednisone. Liver Enzymes Elevated" Lupus Community - Support Group. Elevated liver enzymes - Mayo Clinic. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. I am another one with a diagnosis of UCTD. My symptoms most resemble lupus, but positive ANA is the only specifically associated test that is consistantly positive, other than off and on elevations in Sed rate, CRP and liver enzymes. I had one very mildly positive rheumatoid factor. I've been on Plaquenil for 3 years. Liver enzyme abnormality was defined as a 10-fold or greater increase in aspartate aminotransferase and alanine aminotransferase. Acute toxic hepatitis was diagnosed, which rapidly returned to normal after cessation of the suspected causative medication, hydroxychloroquine, and subsequent administration of mycophenolate mofetil.