I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. Artemisinin and chloroquine structure How does plaquenil affect eyes Hydroxychloroquine plaquenil drug class Hydroxychloroquine myopathy Original Article from The New England Journal of Medicine — Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications Sulfasalazine is a combination of sulfapyridine and aspirin like compounds. The medication may be associated with diminution in complete blood cell count. In general, one should consider withdrawal of the medication three or four days prior to surgery. Hydroxychloroquine is a less commonly utilized disease modifying anti-rheumatic medication. Other conventional DMARDs your doctor may choose include leflunomide, hydroxychloroquine, and sulfasalazine. Like methotrexate, leflunomide can potentially lead to liver damage, although rare, and. I had side effects from MTX, which largely wore off, but haven't had any problems with the Hydroxy or Sulpha. I refuse to take it now even if its my passport to biologic treatment. I started with MTX which worked, but not enough so the others were added in which has been better. Sulfasalazine hydroxychloroquine and methotrexate Methotrexate vs Sulfasalazine Comparison -, A Guide To Perioperative Management Of The Rheumatoid. Hydroxychloroquine eye exam frequencyPlaquenil liver kidney toxicityChloroquine indicationsCan chloroquine injection terminate pregnancy Traditional DMARDs Methotrexate, Leflunomide, Sulfasalazine, Hydroxychloroquine, and Combination Therapies Amy C. Cannella, James R. O’dell Key Points Methotrexate is one of the most durable and frequently used disease-modifying antirheumatic drugs DMARDs in monotherapy as well as the cornerstone of combination therapy for rheumatoid arthritis RA. Traditional DMARDs Methotrexate, Leflunomide.. DMARDs A Treatment Option for RA Everyday Health. REFERENCES - UpToDate. Methotrexate is one of the most durable and frequently used disease-modifying antirheumatic drugs DMARDs in monotherapy as well as the cornerstone of combination therapy for rheumatoid arthritis RA. Leflunomide, sulfasalazine, and hydroxychloroquine are effective therapies in RA and are commonly employed in combination therapy. A 44-year-old woman with seropositive rheumatoid arthritis, on triple-DMARD therapy methotrexate, sulfasalazine, and hydroxychloroquine, presents with a 1.5-cm nodule on her right breast, and no suspicious regional lymph nodes. Hi tere, I take sulphasalazine and hydroxychloroquine in combination with methotrexate, They sometimes give me a slightly dodgy tummy, but nothing unbearable if it gets too problematic I miss 2 or 3 doses and it soon settles again.