One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Reddit plaquenil Plaquenil easy bruising Chloroquine brain cancer And, as far as Plaquenil and eye problems, the Ophthamologists I've talked to including a Neuro Ophthalmologist say that while Plaquenil can cause serious damage to the optic nerve, it's very rare. Annual appointments with an ophthalmologist are important in order to catch any problems early. Full-field ERGs were performed only in selected patients to evaluate the extent of damage beyond the macula. Patient E3 showed reduced cone amplitude in 1 eye only that was of doubtful significance because the flicker response times to peak were normal and symmetrical. Patients M3 and M4 had normal full-field ERG findings. If experienced, these tend to have a Less Severe expression. A Skin Rash; Bleached Hair; Blurred Vision; Decreased Appetite; Diarrhea; Discoloration Of Nail; Discoloration Of The Mouth; Dizziness. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil ful fielderg severe Multifocal ERG in Practice -, Comparison of Screening Procedures in Hydroxychloroquine Toxicity Aao hydroxychloroquine guidelinesRetail cost of plaquenil Worsening of psoriasis and porphyria Use of PLAQUENIL in patients with psoriasis may precipitate a severe attack of psoriasis. When used in patients with porphyria the condition may be exacerbated. When used in patients with porphyria the condition may be exacerbated. Plaquenil Concordia Pharmaceuticals Inc. FDA Package Insert. Common and Rare Side Effects for Plaquenil Oral. PLAQUENIL®. I see my doc in 5 days and rather than do the full 800mg. I'm weaning myself off, before I become suicidal I already want to hurt myself, I'm so depressed, but not suicidal yet. I would recommend Plaquenil for people without or with only mild depressive disorders, but not to someone like me with severe, disabling bipolar disorder. Show Full Comment Comment This medication relieved my joint pain, muscle weakness, myositis, pleuritic pain, and fatigue after about 2-3 months of starting the medication. Dronedarone Severe Dronedarone administration is associated with a dose-related increase in the QTc interval. The increase in QTc is approximately 10 milliseconds at doses of 400 mg twice daily the FDA-approved dose and up to 25 milliseconds at doses of 1600 mg twice daily.