Quinacrine hydrochloride also has the 4-amino quinoline radical but has, in addition, a benzene ring; it is classified as an acridine compound. The 4-amino quinoline radical is present in all antimalarial compounds shown to be effective in the treatment of lupus erythematosus (LE) (Figure). Plaquenil action Chloroquine cas Price hydroxychloroquine 200 mg Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Plaquenil hydroxychloroquine and Aralen chloroquine phosphate are antimalarial medications used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Aralen is also used to treat infections caused by amoebae. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Its superiority over quinine was established during World War II, when it became the official drug for the treatment of malaria. Quinacrine was introduced for malaria therapy in 1930. Hydroxychloroquine vs chloroquine Chloroquine and Hydroxychloroquine Toxicity Practice., Plaquenil vs. Aralen Prescription Treatment for Malaria. Plaquenil hyponatremiaChloroquine resistant area Compare Hydroxychloroquine vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Hydroxychloroquine rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Hydroxychloroquine vs Plaquenil Comparison -. Chloroquine - Wikipedia. Hydroxychloroquine DermNet NZ. What is Hydroxychloroquine, and What Does It Do? According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with can also reduce the incidence of joint damage, thus lessening the risk of developing a long-term disability from complications. What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. In contrast, of the 66 patients receiving hydroxychloroquine, none developed retinopathy. Retinopathy was associated with greater age and with greater accumulative doses of chloroquine. Thus, hydroxychloroquine can be used safely with minimal risk of toxicity.