Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Artemisia annua plaquenil Drugs for chloroquine resistant malaria Plaquenil cumulative dose toxicity retina Dr. Noskow’s Case Report Plaquenil Toxicity Why it’s important to get your eyes routinely checked when on certain high- risk medications! What is plaquenil? Plaquenil is a medication commonly used in patients that have Rheumatoid Arthritis RA, Systemic Lupus Erythematosus SLE, Sjogrens Syndrome, and other inflammatory and autoiummune disorders. What are risk factors for developing SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. High risk medication use plaquenil Protecting your eyesight when taking Plaquenil Lupus., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Btk calcium chloroquineOrder aralen lupus Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. The Risk of Retinal Toxicity with Plaquenil. Plaquenil Risk Calculators. ICD-9-CM Diagnosis Code V58.69 Long-term current use of.. If the patient is seen while using a high-risk medication such as Plaquenil, code the reason for the visit first as V58.69 long-term current use of other high-risk medications, says Roberts. If the patient is seen after the completion of a high-risk medication course of treatment, use V67.51 follow-up examination; following completed. How to use Plaquenil. Use this medication regularly in order to get the most benefit from it. If you are taking it on a daily schedule, take it at the same time each day. This risk may. Free, official coding info for 2020 ICD-10-CM Z79.899 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.