Chloroquine bull's eye maculopathy guidelines

Discussion in 'Chloroquine Drug' started by manov, 16-Mar-2020.

  1. Rishat Guest

    Chloroquine bull's eye maculopathy guidelines


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Apr 20, 2011 Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Hydroxychloroquine or chloroquine ingestion can cause atrophy of the retinal pigment epithelium in the form of a bull’s eye maculopathy in cases of chronic use. Early detection of toxicity prior to the development of the bull’s eye is important, as loss of visual acuity is usually irreversible at that stage. My Take on New Ocular Screening Guidelines for Plaquenil By Sergio Schwartzman, MD 12 October 2016 A recent article published by the American Academy of Ophthalmology AAO presented new recommendations for screening of patients being managed with hydroxychloroquine HCQ.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Chloroquine bull's eye maculopathy guidelines

    Retinal Physician - Hydroxychloroquine Maculopathy An., Macular Telangiectasia A cause of bull’s eye maculopathy

  2. Chloroquine selleck
  3. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and

    • Hydroxychloroquine And Chloroquine Screening 2016 AAO..
    • My Take on New Ocular Screening Guidelines for Plaquenil..
    • Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy.

    Later in the disease, patients can develop a bilateral bull's eye maculopathy, characterized by a ring of retinal pigment epithelium RPE depigmentation in the macula, sparing the fovea, which is often accompanied by paracentral and central scotomas. End stage hydroxychloroquine toxicity leads to widespread RPE and retinal atrophy with a loss of central vision, peripheral vision, and night vision. Bull’s eye maculopathy is a rare dystrophy, also known as benign concentric annular macular dystrophy BCAMD. It causes a dartboard, or ring-shaped, a pattern of damage around the macula. This characteristic damage can also be caused by other inherited retinal conditions, or by long-term use of drugs which suppress the immune system as part of treatment for lupus or rheumatoid arthritis. Dec 27 2013 by David Callanan, MD 59yr old patient. Had several courses of chloroquine for malaria; native of Africa. Condition/keywords bull's eye maculopathy, chloroquine

     
  4. pups XenForo Moderator

    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. PATIENT FACT SHEET Hydroxychloroquine Plaquenil Hydroxychloroquine sulfate Pill Images - What does. Hydroxychloroquine Uses, Dosage & Side Effects -
     
  5. klim_ Well-Known Member

    Chloroquine Phosphate - Usages, effets secondaires, Avis. Si vous éprouvez de la somnolence, des vertiges, l'hypotension ou des maux de tête comme des effets secondaires lorsque vous mangez le médicament Chloroquine Phosphate alors il peut ne pas être sûr de conduire un véhicule ou d'utiliser des machines lourdes.

    Aquarium Fish Chloroquine A "New" Drug for Treating Fish.