I have been on plaquenil for over a year and a half and methotrexate since September. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes (used to be every 2 weeks). I have lupus which mainly affects my joints and skin. One affects your eyes more and one affects your liver more. I would appreciate any comments or advice from everyone. Wannabe Hi, I am on both methotrexate and plaquenil. Wannabe To Be Free To Roam Sorry to hear that you are having a lot of pain with your RA. Chloroquine phostate for ich Guttate psoriasis plaquenil I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it. The first two weeks weren't bad, as Plaquenil has a high half-life and there was still some Plaquenil in my body. After that, my Lupus got progressively worse until I gave up and re-started the Plaquenil after 6 weeks of being off it. Hi everyone! I'm a fairly new methotrexate and hydroxychloroquine user started both in mid-December of last year and am due to go on holiday in Florida on Saturday. There have been a number of coronavirus cases in Florida and two deaths there from the illness. Being on immunosuppressants I'm a little nervous to be travelling there. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Taking methotrexate with hydroxychloroquine has not been studied. It may increase your risk of side. I wish you well with this decision and the results. Your chances of problems with the methotrexate are a bit larger. deductible (I am at about $2,500 - $3,000 right now). My rheumy recently added Imuran (instead of methotrexate). So, what do yall know about the side effects of both and the benefits of both? Methotrexate and hydroxychloroquine Methotrexate vs Plaquenil Comparison -, Methotrexate and coronavirus rheumatoid Plaquenil for uti Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Plaquenil hydroxychloroquine sulfate dose, indications, adverse.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Methotrexate and Coronavirus Apologies if this. - LUPUS UK. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Curcumin in turmeric may increase the therapeutic action of arthritis medications and protect from their side effects as well. Let’s examine the scientific details behind the safety of taking turmeric and curcumin with arthritis medications. 1. Curcumin may change drug absorption. Turmeric and curcumin are safe for consumption. OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone.