It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine sulfate solubility Synthesis of chloroquine from m-chloroaniline BACKGROUND Hydroxychloroquine is used for the treatment of rheumatoid arthritis RA and systemic lupus erythematosus SLE. Long term studies have shown a high rate of termination of hydroxychloroquine treatment in patients with RA. Long-Term Additive Cardiovascular Benefit of Plaquenil and Aspirin in Lupus By Jack Cush, MD 17 July 2017 Systemic lupus erythematosus SLE is associated with an increased risk of cardiovascular disease CVD. Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Long term effects of plaquenil Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Long-Term Additive Cardiovascular Benefit of Plaquenil and. Plaquenil depressedChloroquine stabilityHydroxychloroquine human antihimeric antibodiesPlaquenil for inflammatory arthritisCan hydroxychloroquine cause insomnia Feb 20, 2018 Plaquenil is taken by mouth with food or milk to prevent stomach problems. When taking this medication, some patients may experience upset stomach, nausea, loss of appetite, headaches or dizziness. Sometimes, taking high doses or long-term treatment of Plaquenil can lead to vision problems. Focus on Eyes Long-term Plaquenil intake can affect your vision. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Retinal Damage. Neurological Disorders. Blood Disorders. Hearing Disorders. Other Side Effects. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.