Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine memory loss Hydroxychloroquine makes me feel worse Hydroxychloroquine topical The other suggestion would be to try taking your plaquenil one with breakfast and one with dinner or night time snack. You could even take one and a half each day for a couple weeks and then go up to the full two pills. Plaquenil usually takes several weeks to kick it in. It has to build in the system. I have been on plaquenil for over a month. Every night my dreams are so crazy but so realistic. I know nightmares are a side effect but does it get any better with time? They are really shaking me up. If however you have lyme bad enough to be on months of plaquenil, isn't it almost better to be getting the treatment with some bad dreams, than having no bad dreams but continuing with lyme disease? Unless of couse you can switch to another that'll work as well clarythromicin has worked well. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil bad dreams Plaquenil nightmares anyone? Do they ever go away? lupus, Plaquenil side effects - @Jamie76 - Scleroderma - 20130924. B6 and plaquenilPlaquenil psoriatic arthritisVision changes to watch for on plaquenilHydroxychloroquine brand name in pakistanDoes plaquenil have lifetime effects Despite being a fairly common occurrence in many people’s lives, bad dreams and nightmares still remain somewhat of a mystery to neuroscientists and psychologists. It is believed that bad dreams could possibly be an unconscious reflection of trauma or stress experienced during waking life, or perhaps even be an indicator of physiological disorders like sleep apnea. Violent Nightmares Are An Unconscious Warning of Brain Disease. Plaquenil as lyme treatment Anti-Inflammatories.. Hydroxychloroquine Sulfate Dysgeusia Reports - DrugInformer. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have had any eye changes or changes in eyesight due to this drug or drugs like this one. If you have psoriasis. I could not sleep while taking it, if I did I had horrible dreams. I was nauseus the entire time and had horrible headaches. After a month and a half-and being very depressed-actually ready to jump out a window--no kidding--I stopped the plaquenil--cold turkey. The bad dreams stopped, I was sleeping again, still have some stomach problems.