At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. Hydroxychloroquine effect on platelets Chloroquine phosphate saltwater Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Hi CatJ - I was also on that combination for 6 months but came off the Hydrox as it wasn't working for me and it also caused trouble with my eyes. However, that eventually settled down once not taking it any more. Had to see the eye surgeon at the hospital. No treatment required. Had spots on the corneas which the optician first noticed. Hydroxychloroquine should not be taken with other drugs that could cause heart arrhythmias irregular heart rate or rhythm. Taking hydroxychloroquine with these drugs could cause dangerous. I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Hydroxychloroquine not working Hydroxychloroquine — Arthritis Australia, Does anyone take methotrexate and hydroxychloroquine. How does plaquenil affect eyesSide effects of long term use of plaquenilEasy bruising plaquenilCorticosteroids vs plaquenil Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. If you experience any of the following symptoms while taking hydroxychloroquine, call your doctor immediately 5 problems seeing or reading including if words, letters, or parts of objects are missing. light sensitivity. blurred distance vision. seeing light flashes or streaks. difficulty. Have you followed up with your dr about the swelling if not you might want to. I know it takes a couple of days for the preisone to get in your system. Give the doc a call and see what they say; they might not be able to get you an appt but they can tell you if it is something you should be concerned about or not. Re Plaquenil not working anymore Lizzy, I took 400mg 200 twice a day for 16-18 months forget exact duration, then was reduced to 200 mg daily. But right from the start, I also needed NSAID's for pain.