I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. Still get mysterious rashes, fevers and other odd symptoms. Asked my primary to check my thyroid after taking a bovine herbal thyroid med for 2 weeks. Then they worked out it was my liver causing my liver and that I could go back on Plaquenil. I have gained nearly 25 lbs now and I can' t stand it, but when I try an dexercise it is as if my muscles just will not relax, the are tight and it hurts to even do the lightest yogo! I took 60mg for a year and only 30 this past month. NOw if my thyroid isn't working I've hidden it from my dr... Well, within 3 days my non-liver symptoms were way better. Chloroquine 250 mg Plaquenil cause hair loss reddit This is a new question concerning an old post. Plaquenil and muscle pain. I thought that maybe my question had been answered when I read that Plaquenil was responsible for your muscle pain but, as I read on I realize it was not. I TOO have severe muscle pain and cramping in my legs. Only when trying to sleep. Drug-related myotoxicities such as rhabdomyolysis or myoglobinuria are more typically reported, as they are more serious medical emergencies. Rhabdomyolysis is a fulminant and acute, necrotizing myopathy that can cause severe pain, muscle swelling and weakness, and elevated serum CK as high as 2000 times the upper limit of normal. Sep 24, 2010 I went in to my Rheum this week because I was having a lot more pain, burning, and muscle fatigue, particularly in my legs and arms, especially at night while I'm trying to sleep. He told me to stop the Plaquenil because sometimes it can cause nerve damage. He told me to stop it for two weeks and come back in. He said nerve damage is a side effect. I saw a rheumatologist who said "no the nausea is at the start before you get use to it etc, but just come off it for 2 weeks to 'prove this doctor wrong'". Don't know what I was thinking but my thyroid showed 1.59 (0,47-4.68)... Since then I've had one flare up of my hips and finger joints, which lasted for about 2-3 days (typically my flares last a few weeks). I'd say they're 90-95% better than this time last year. Plaquenil cause muscle pain Plaquenil for fatigue and pain DailyStrength, Drug-related Myopathies of Which the Clinician Should Be Aware Chloroquine for alzheimer's disease treatmentIs plaquenil used to treat fibromyalgiaNatural substitute for plaquenil for discoid lupus Do you still have joint and muscle pain on plaquenil? I've been on plaquenil for 6 months now and I still have significant joint pain! I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. Lupus Do you still have joint and muscle pain on plaquenil?. Plaquenil and nerve damage - Scleroderma - Inspire. Can Plaquenil cause Muscle Weakness? - Treato. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells.