Please consider using the search field or links below to navigate to the desired page on , an antimalarial drug, is traditionally used in the treatment of SLE. Can plaquenil cause weight gain Chloroquine prostate cancer Is plaquenil a immunosuppressant Hydroxychloroquine diagnostic tests The mechanisms of action of hydroxychloroquine and chloroquine remain under continuous study in modern molecular medicine 17,18 using advanced tools in computational biology 19, synthetic biology. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Precise mechanism of action is not known. INDICATIONS PLAQUENIL is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis. In vitro and in vivo studies showed a beneficial effect of hydroxychloroquine on thrombosis . Its effectiveness in treating APS has been previously questioned. Plaquenil for lupus mechanism Plaquenil hydroxychloroquine sulfate dose, indications., Hydroxychloroquine Plaquenil - Chloroquine concentration lysosomePlaquenil drowsinessChloroquine sulphate structure The mechanism of action is thought to be anti-inflammatory, but Plaquenil also seems to reduce sensitivity to sunlight. It has also been noted recently that smoking reduces the effectiveness of Plaquenil in treating lupus, thus, smoking cessation should be instituted in all patients taking Plaquenil. More About Autoimmune diseases DERMATOMYOSITIS Plaquenil Use in Autoimmune Diseases. PLAQUENIL®. Plaquenil. A medication for Lupus. Mechanism of Action of Hydroxychloroquine as an Antirheumatic Drug By Robert I. Fox The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. Hydroxychloroquine, mortality, survival, systemic lupus erythematosus Antimalarials, particularly hydroxychloroquine, have proven beneficial effects beyond the control of disease activity among systemic lupus erythematosus patients. Indeed, recent data support the notion that prolonged treatment with hydroxychloroquine prevents damage accrual.