I have been getting these horrible rashes and they are not related to sun exposure. I am starting to wonder if they are related to Plaquenil. Hydroxychloroquine rheumatoid arthritis moa Missed dose of plaquenil Plaquenil tablet image Chloroquine marine ich Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. A very serious allergic reaction to. Thanks for the info--I am taking the generic form. My info said that a rash was a sign of a "very serious allergic reaction" I don't feel like it was an emergency situation. Its funny, because it itched a little at first and then it stopped. About 30 mins later the whole rash was gone. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I've always been one to go for the natural route and am starting to feel like I should just stop taking everything and see what happens - so frustrating. My doctor now wants me to start on Chloroquine instead of plaquenil. Allergy reaction to plaquenil Plaquenil and Sulfa Allergies" Lupus Community - Support., Immune & Autoimmune - Lupus Anyone Get An Itchy Rash From Plaquenil generic and brand names She said that plaquenil was the least likely to cause liver issues. I did read that there is a small possibility that was maybe the brand. Has anyone had a reaction to the generic, but then did ok with the name brand Plaquenil? Or anyone else that had such a severe reaction to Hydroxycloroquine but did well with another med entirely? Allergic reaction to Plaquenil Lupus Forums at The Lupus Site. Plaquenil Side Effects Common, Severe, Long Term -. Allergic reaction to plaquenil DailyStrength. It does sound as though u have a allergic reaction. I hope anti histamine doesn't take the edge off the itching this is very important to report to UR doc. He can give u recommendations for dealing with the rash itching reaction by RX the appropiate antihistamine. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.