I am asking this question, because I started this med approx. 1 month ago and prior to taking it I rarely ever got sick with colds,flu etc. Chloroquine define Plaquenil for lichen planus Plaquenil and hydrea Suppressed Immune system because of steroids and 12.5 methotrexate. Thanks Immune system happy Christmas to you too. Oral surgeon says \"Breeding ground for bacteria\" and \"your immune system must be taking a beating\" Hydroxychloroquine ; Hydroxychloroquine Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. it’s believed that this drug affects how your immune system works, which may be a benefit in lupus. All of my symtoms pretty much cleared up. Now this year I have been having things pop up that are related to a low immune system. Some of my doctors think It is the Plaquenil causing it but then some say that Plaquenil is not an immunosuppressant drug that for some reason my immune system is out of wack. I only take 200 mg a day. Around 2 weeks ago, I came down with a doozy of an illness (flulike with croup like cough that just won't quit). The only thing that usually ever ailed me were the crappy Sjogrens symptoms. Does hydroxychloroquine lower immune system Anyone on Hydroxychloroquine plaquenil - Autoimmune diseases - Inspire, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil dermatomyositis Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic. Is Plaquenil a immunosuppressant drug ? Autoimmune.. Hydroxychloroquine - Wikipedia. How does Plaquenil work? Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk. The mechanism is unknown. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Machanic on does hydroxychloroquine suppress the immune system been shown to affect the immune system. It tends to weaken it.