Please review the following URL and make sure that it is spelled correctly. Hi - I just started Plaquenil (400 mg a day) two week ago and I started feeling less achy and tired a few days ago. Hydroxychloroquine monitoring bloods Hydroxychloroquine generic and brand names Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Reviews and ratings for plaquenil when used in the treatment of rheumatoid arthritis. I rated it an 8 because I do not feel sick after taking it and it does seem to work. "This medication did wonders for my soreness and pain from Rheumatoid Arthritis but if someone would have told me I would have devastating and. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Is it possible for it to work quicker in some people? Does plaquenil work Plaquenil Hydroxychloroquine - Side Effects, Dosage., How Does Plaquenil Work For Rheumatoid Arthritis Hydroxychloroquine yellow Mar 24, 2011 Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it. What next if plaquenil doesn't work? -. Plaquenil - Uses, Side Effects, Interactions -. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. this drug is also effective at preventing lupus flares. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. When treating lupus or arthritis, Plaquenil is usually given daily for several weeks or months. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 months of treatment. While using Plaquenil, you may need frequent blood tests and vision exams.